Big 100 2016: A look at the World’s 100 largest Medtech companies.

It’s September, and here at Medical Design & Outsourcing that means it’s time for the Big 100, our annual look at the largest players in the medical technology world.

Actually, around here Big 100 time started months ago, when we began scouring regulatory filings and annual reports. Here you’ll find the result, information on the world’s 100 leading medical technology companies, ranked according to annual revenues, plus rankings according to R&D spend and number of employees.

The Big 100 also includes a look at executives’ notable moves into – and out of – the corner office, and maps showing medical technology hotspots in the U.S. and around the world. And this year we’re providing a glimpse at 10 companies that could make the jump to the 2017 Big 100.

In compiling the issue, we used data from the most recently concluded fiscal year for each company, plus information from our own archives, corporate documents and public regulatory filings and the companies’ websites.

For diversified companies like Johnson & Johnson, which have businesses in non-medical device areas, we took into account only the numbers reported for their medtechrelated
businesses (J&J made that much easier this year by ditching its Ortho-Clinical Diagnostics business to focus on devices).

We used the 2015 average exchange rates set by the U.S. Federal Reserve to calculate U.S. dollar conversions for companies that report in other currencies.

Last year once again featured lots of churn along the list, as companies acquired and were acquired in an M&D feeding frenzy. Most notably, Medtronic’s acquisition of Covidien pushed it into the top spot this year, displacing Johnson & Johnson for the first time since we began compiling the list in 2011.

Likewise, Becton Dickinson’s buyout of CareFusion pushed it from 37th to 8th on the list; Abbott vaulted from 45th last year to 23rd this year (and that doesn’t even account for its pending $25 billion pickup of St. Jude Medical).

Other companies, such as Cook Medical, Ottobock and Hanger Orthopedic, would likely have made the list had they posted results for 2015 (the German prosthetics giant is reportedly preparing to take itself public). But again acquisitions played the largest role, taking these companies off the table:

• Allergan (acquired by Actavis)
• Arseus (acquired by Henry Schein)
• Arthrocare (acquired by Smith & Nephew)
brad-p-medtech-big-100• Biomet (acquired by Zimmer)
• Endo Health Solutions (exited devices with the sale of its American Medical Systems urology business to Boston Scientific)
• Hospira (acquired by Pfizer)
• Medical Action Industries (acquired by Owens & Minor)
• Mindray Medical (taken private by management)
• Nobel Biocare (acquired by Danaher)
• Symmetry Medical (acquired by Tecomet)
• Toshiba Medical Systems (dealt to Canon)
• Volcano (acquired by Philips)
• Welch Allyn (acquired by Hill-Rom)

RANK COMPANY 2014 Revenues 2014 R&D Spend Employees
1 Medtronic $28,833,000,000 $1,640,000,000 92,000
2 Johnson & Johnson $25,137,000,000 $9,046,000,000 127,100
3 Philips Healthcare $19,817,952,415 $2,175,322,855 104,204
4 GE Healthcare $17,639,000,000 $0 333,000
5 Fresenius Medical Care $16,739,425,600 $305,969,147 33,195
6 Siemens Healthcare $11,652,847,873 $4,500,000,000 348,000
7 Cardinal Health $11,395,000,000 $0 34,500
8 Becton, Dickinson and Co $10,282,000,000 $632,000,000 45,000
9 Baxter International $9,968,000,000 $603,000,000 50,000
10 Stryker Corp $9,946,000,000 $625,000,000 27,000
11 Alcon $9,812,000,000 $7,232,000,000 118,700
12 Owens & Minor $9,772,946,000 $0 8,100
13 Danaher $8,213,100,000 $1,239,100,000 81,000
14 Fujifilm Holdings $7,895,225,114 $0 n/a
15 Bayer $7,792,720,800 $3,140,070,000 116,800
16 Boston Scientific $7,477,000,000 $876,000,000 25,000
17 Essilor International $7,452,073,600 $221,920,000 61,000
18 B. Braun Melsungen $6,801,626,080 $288,351,648 54,770
19 Zimmer-Biomet $5,997,800,000 $4,500,000 17,500
20 Hitachi $5,625,774,473 $92,120,000 335,244
21 St. Jude Medical $5,541,000,000 $676,000,000 18,000
22 3M Co. $5,420,000,000 $12,000,000 35,973
23 Olympus Corp $5,030,375,878 $424,575,200 16,728
24 Abbott Laboratories $5,000,000,000 $1,405,000,000 74,000
25 Smith and Nephew $4,634,000,000 $222,000,000 15,644
26 Cerner $4,425,000,000 $685,000,000 22,200
27 Grifols $4,365,832,160 $246,205,217 14,737
28 Terumo $4,043,833,127 $286,981,780 19,934
29 Getinge Group $3,584,469,472 $0 15,000
30 C.R. Bard $3,416,000,000 $254,700,000 14,900
31 Varian Medical Systems $3,099,100,000 $245,200,000 7,300
32 McKesson $2,885,000,000 $392,000,000 68,000
33 Hologic $2,705,000,000 $213,695,000 5,290
34 Dentsply International $2,674,300,000 $74,900,000 11,400
35 Hoya $2,532,837,670 $181,603,800 34,635
36 Edwards Lifesciences $2,493,700,000 $383,100,000 9,800
37 Intuitive Surgical $2,384,400,000 $197,400,000 3,211
38 Steris $2,238,764,000 $56,664,000 14,000
39 BioMerieux $2,180,364,000 $265,290,000 9,375
40 Coloplast $2,067,853,054 $65,712,204 9,303
41 Paul Hartmann Group $2,067,510,000 $ 10,001
42 Waters $2,042,332,000 $118,545,000 6,600
43 Bio-Rad $2,019,400,000 $193,000,000 7,800
44 Sonova Holding $1,994,854,204 $125,409,514 10,697
45 Hill-Rom Holdings $1,988,200,000 $91,800,000 10,000
46 Nipro $1,964,477,489 $0 24,243
47 Draegerwerk $1,826,401,600 $44,162,080 n/a
48 Teleflex $1,809,690,000 $52,100,000 12,200
49 The Cooper Cos. $1,797,060,000 $69,600,000 10,200
50 Miraca Holdings $1,749,219,331 $0 n/a
51 ResMed $1,678,912,000 $114,865,000 4,340
52 ConvaTec $1,650,500,000 $41,200,000 9,100
53 Bruker $1,623,800,000 $145,700,000 6,000
54 IDEXX Labs $1,601,892,000 $99,681,000 6,800
55 William Demant Holding $1,585,567,102 $0 10,803
56 Halyard Health $1,574,400,000 $32,300,000 12,000
57 Nihon Kohden $1,367,385,378 $48,822,800 4,776
58 Elekta $1,330,290,456 $126,259,632 3,600
59 Smiths Medical $1,277,742,400 $141,790,000 23,250
60 Agfa-Gevaert $1,219,450,400 $99,864,000 10,241
61 Sirona Dental Systems $1,161,300,000 $54,800,000 3,458
62 Carl Zeiss Meditec $1,154,051,686 $124,227,487 2,888
63 Amplifon $1,147,300,879 $0 6,333
64 Invacare $1,142,338,000 $18,677,000 4,700
65 DJO Global $1,113,627,000 $35,105,000 5,260
66 Fukuda Denshi $968,376,704 $34,266,832 3,422
67 Haemonetics $910,373,000 $54,187,000 3,383
68 Omron $895,704,254 $ n/a
69 Integra Lifesciences $882,734,000 $50,895,000 3,500
70 Cochlear Ltd. $871,122,820 $107,564,600 2,934
71 Align Technology $845,486,000 $61,200,000 4,375
72 Kawanishi Holdings $838,166,047 $0 n/a
73 NuVasive $811,113,000 $35,851,000 1,600
74 Greatbatch $800,414,000 $52,995,000 9,559
75 GN Store Nord $769,368,003 $0 4,100
76 Straumann $768,892,080 $221,340,000 3,471
77 Acelity $745,457,000 $55,950,700 1,000
78 Konica Minolta Holdings $741,842,214 $0 43,332
79 Conmed $719,168,000 $27,436,000 3,400
80 LivaNova (formerly Sorin/Cyberonics) $707,265,000 $95,215,000 4,700
81 Masimo $599,334,000 $56,617,000 2,400
82 Fisher and Paykel $570,923,149 $51,308,929 3,587
83 Cantel Medical $565,004,000 $92,000,000 1,680
84 Merit Medical Systems $542,149,000 $40,810 3,754
85 Össur $483,034,000 $18,361,000 2,525
86 Thoratec $477,560,000 $105,475,000 1,048
87 JMS Co. $457,859,000 $13,605,948 6,777
88 Wright Medical $415,461,000 $39,855,000 2,295
89 DexCom $402,000,000 $137,500,000 1,212
90 Orthofix International $396,489,000 $26,389,000 927
91 Accuray $379,801,000 $55,752,000 1,010
92 Natus $375,865,000 $30,434,000 1,067
93 Topcon $362,114,829 $0 n/a
94 Nikkiso $343,593,556 $0 n/a
95 ICU Medical $341,254,000 $15,714,000 2,446
96 CynoSure $339,462,000 $22,343,000 857
97 NxStage Medical $336,123,000 $26,237,000 3,600
98 Abiomed $329,520,000 $49,759,000 152
99 Insulet $324,225,000 $43,208,000 647
100 RTI Surgical $282,293,000 $15,065,000 1,169
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