Are nanoparticles overhyped?

Young startups backed by nanoparticle tech face a world hurdles before reaching the clinic. It’s been decades since the first innovations with nanotechnology – and experts are asking, “Where are all the drugs?” It’s been more than 20 years since the FDA approved the first nanoparticle drug, Doxil. At the time, nanoparticles were heralded as a

Vetter, Microdermics ink deal to develop novel microneedle drug delivery system

Prefilled drug delivery system developer Vetter and medical device maker Microdermics said yesterday that the companies are working to develop a novel microneedle drug delivery system. Microdermics has developed a low-cost, commercially scalable, customizable microneedle platform that delivers vaccines and biologics. The company said it expects its intradermal delivery system will enter Phase I clinical trials this

9 diabetes breakthroughs you need to know

Diabetes is a disease that affects the body’s ability to produce and respond to insulin. About 29.1 million people have diabetes in the U.S, according to the Centers for Disease Control and Prevention. Of that number, 8.1 million go undiagnosed. One of the most popular breakthroughs in diabetes research has been the artificial pancreas, which

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Artificial pancreas: These companies are racing to make one

Medical device companies are close to achieving the holy grail of diabetes treatment: a combined glucose sensor, control algorithm and insulin infusion device that effectively acts as an “artificial pancreas.” We explain more in our newest Medical Design & Outsourcing video. (And for a deeper dive, check out our recent roundup of companies in the

Raumedic touts customized silicone syringe plungers

Raumedic has released customized syringe plungers made of silicone that come in a wide range of designs. Syringe plungers made of silicone allow for precise dosing of the drug being administered. Other advantages of this material include its physical/mechanical properties and the high chemical purity of its formulation. Last but not least, silicone allows for

FDA approves first ALS treatment in over 2 decades

The FDA recently announced that it has approved the drug Radicava (edaravone) to help treat patients who have amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. ALS is a progressive neurodegenerative disease that affects the nerve cells in the brain and spinal cord, according to the ALS Association. Motor neurons in the brain

Wireless power source could enable ingestible drug delivery devices

Researchers from the Massachusetts Institute of Technology, Brigham and Women’s Hospital and the Charles Stark Draper Laboratory have developed the means to wirelessly power electronic devices that stay in the digestive tract indefinitely. The team suggests that these devices could be used as sensors in the GI tract or carry drugs to be delivered over

How Boston Sci is getting drug-eluting stents and balloons into legs

Boston Scientific officials think they have a leg up when it comes to bringing drug-eluting technology to bear on peripheral artery disease. That’s because the medical device giant has decades of experience with balloons and drug-eluting stents used around the heart. When it comes to treating the narrowing arteries in the legs and thighs, Boston

5 things you need to know to make connected medical devices

Bill Welch, Phillips-Medisize The estimated number of connected medical devices – devices connected to the Internet –is expected to increase from 10 billion to 50 billion over the next decade, according to the IBM Institute for Business Value. This is due to the ability for machine-to-machine communication through cloud computing and networks of data-gathering sensors,

7 companies in the race to make an artificial pancreas

Over 50 years ago, scientists discovered the ability to externally control blood glucose regulation for individuals with type 1 diabetes. Since then, researchers in the field of diabetes management have dreamt of creating a closed-loop system – a combined glucose sensor, control algorithm and insulin infusion device – to effectively act as an “artificial pancreas”

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The stem cell ‘skin gun’ that’s aiming to disrupt wound care

RenovaCare’s SkinGun uses a patient’s own stem cells to heal their wounds faster and more efficiently than a traditional skin graft. Pennsylvania state police officer Matthew Uram suffered severe second-degree burns to his face, right arm and leg after a friend’s bonfire got out of control. Uram was facing months of painful skin grafts, the

The stem cell therapy that could reverse hearing loss

Frequency Therapeutics is betting that it can change the lives of millions of Americans with hearing loss through a cell therapy that triggers the body’s natural ability to heal itself. Researchers have used cells in regenerative medicine for decades – in 1931, the father of cell therapy, Paul Niehans, treated a patient with material from

Fibrosis: How to prevent it in medical device implants

Massachusetts Institute of Technology (MIT) and Boston Children’s Hospital researchers have discovered a way to prevent fibrosis from forming around medical device implants. The body’s immune system usually attacks implanted medical devices that are used for drug delivery, sensing or tissue regeneration. Defense cells in the body try to isolate the foreign material from devices

These tiny jet engines could propel pharmaceuticals in the body

Researchers at the Max Planck Institute for Intelligent Systems in Stuttgart, Germany are creating nanorobot propulsion systems that could help transport pharmaceutical agents in the body. Two types of propulsion systems were created. One was powered by bubbles that are oscillated by ultrasound, while the other one was powered by an enzymatic reaction that would

3D printing is taking medical marijuana to a whole new level

3D printing is aiding an Israel-based company in the development and production of special selective-dose inhalers for medical marijuana and other medicinal plants. Nano Dimension (Ness Ziona, Israel)—which makes 3D printers for printed circuit boards—announced today that it has leased a DragonFly 2020 3D printer to Syqe Medical (Tel Aviv, Israel). Syqe boasts that it has created the