Is this the key to rapidly manufacturing heart valves?

Nanofiber fabrication may be the key to rapidly manufacturing heart valves with regenerative and growth potential, according to new research from Harvard University’s Wyss Institute for Biologically Inspired Engineering. A research team led by Kevin Kit Parker created a valve-shaped nanofiber network that replicates the mechanical and chemical properties of the native valve extracellular matrix (ECM).

Cells can be programmed into living devices: Here’s how

Synthetic biologists at Harvard University have programmed microbial cells into living devices that can produce drugs, fine chemicals and biofuels and detect disease-causing agents. A team of biologists at Harvard’s Wyss Institute for Biologically Inspired Engineering fit cells with artificial molecular machinery that could sense stimuli like toxins in the environment, metabolite levels and inflammatory

Soft, water-powered robot makes endoscopic surgery easier

Harvard researchers have created a rigid-soft robotic arm for endoscopes that can sense, flex and has multiple degrees of freedom. Flexible endoscopes fit through narrow passages to reach difficult parts of the body. Once they reach their target, the devices need rigid surgical tools to be able to manipulate or remove tissues. Researchers from Harvard’s

These fabric-based sensors move with the body

Researchers have designed a new silicone-fabric sensor that can move with the human body and be used in wearables and robotics, according to research from Harvard University’s Wyss Institute for Biologically Inspired Engineering and the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS). Typical sensors that are used on wearables like heart

Electronic organs-on-chips non-invasively measure cell health

It’s possible to embed electrodes onto organs-on-chips to noninvasively monitor tissue health and differentiation, according to new research from Harvard University. Researchers are using organs-on-chips more frequently to study human organs and tissues. They offer a better approach to testing drugs because they can mimic blood flow, mechanical microenvironment and how different tissues are able

How stem cells are creating kidney filtration on a chip

Harvard researchers have developed a glomerulus membrane to mimic the kidney’s filtration system in vitro by using engineered human stem cells. The glomerulus is a structure that has podocyte cells that tightly wrap around capillaries. The cells and the capillaries are separated by a thin membrane of extracellular matrix and between them, a filtration barrier