Cell stacking technology creates living human organs

Research engineers at Brown University have figured out a way to build tiny versions of human organs one micro-level at a time, and Igus technology helped enable the innovation. Using cells that are shaped as microscopic honeycomb-like patterns, Jeffrey Morgan, a professor at the university, created a method that consists of precisely stacking molded cells and

How a common hospital tool predicts poor outcomes after liver transplants

A frequently used tool in the hospital can be an indicator of which liver transplant recipients will do poorly after surgery, according to new research from Cedars-Sinai Medical Center. Led by Vinay Sundaram, a team of researchers found that the nursing assessment called the Braden Scale could be put to use in liver transplant patients

Lab-engineered tissue is creating new digestive tract treatments

Wake Forest Baptist Medical Center have reported success with lab-engineered tissue replacements to treat digestive system diseases. The research team demonstrated the effectiveness of growing anal sphincters in a lab to treat an animal model for fecal incontinence. The success comes after the researchers reported success in implanting human-engineered intestines in rodents. “Results from both

Hydrogel tech boosts success of transplanted insulin-producing cells

A hydrogel material embedded with a protein to improve blood vessel growth may boost the success rate of transplanting insulin-producing islet cells into patients with Type I diabetes, according to a preclinical study published in the journal Science Advances.  In the newly-published work, supported by the National Institutes of Health and the Juvenile Diabetes Research Foundation,

Engineered tissue could eliminate radiation for bone marrow transplants

University of California San Diego engineers have created artificial bone tissue that could eliminate the need for radiation before bone marrow transplants. Shyni Varghese, a bioengineering professor at UC San Diego Jacobs School of Engineering, led a team to develop a bone-like implant to eliminate the pre-treatment radiation that kills stem cells in a patient’s bone

eGenesis raises $38m for CRISPR-powered xenotransplantation

A Cambridge, MA.-based firm got a $38 million boost towards it goal of harvesting animal organs to give to humans in dire need of a transplant. eGenesis, a spin-out from Harvard University, hopes to improve the supply of organs for patients that are stuck on the transplant waiting list. While the seemingly science-fiction field of xenotransplantation

Here’s how you heat up cold hearts—for transplantation

A University of Minnesota–led research team has successfully warmed large-scale animal heart valves and blood vessels that were previously preserved at low temperatures. The discovery of this rewarming process is pivotal for organs and tissues that are left in storage for transplantation for extended periods. “This is the first time that anyone has been able

Egypt arrests 45 in organ smuggling ring

Egypt has uncovered a network accused of illicit international trafficking in human organs, arresting 45 people and recovering millions of dollars in a dawn raid on Tuesday, the health ministry said. Among those held were doctors, nurses, middlemen and organ-buyers, involved in what the ministry described as the largest organ-trafficking network exposed in Egypt to

Tissue-engineered human liver made from stem & progenitor cells

Researchers at the Saban Research Institute of Children’s Hospital in Los Angeles generated mouse and human tissue-engineered livers from organoid units composed of stem and progenitor cells, according to a study published in Stem Cells Translational Medicine last month. The tissue-engineered liver demonstrated normal attributes such as hepatocytes and blood cells and even restored some

Medicaid expansion increased Medicaid enrollment among liver transplant recipients

Researchers have found that Medicaid expansion increased Medicaid enrollment among people who received liver transplants funded by commercial insurance. The findings are published in Liver Transplantation. Because liver transplant recipients in the U.S. have low rates of paid employment, many are eligible for Medicaid public health insurance after their surgery. In a new study, Dmitry Tumin,

Insect wings inspire antibacterial surfaces for corneal transplants, other medical devices

Someday, cicadas and dragonflies might save your sight. The key to this power lies in their wings, which are coated with a forest of tiny pointed pillars that impale and kill bacterial cells unlucky enough to land on them. Now, scientists report they have replicated these antibacterial nanopillars on synthetic polymers that are being developed

Cell Applications, Cyfuse launch 3D bioprinting method in North America

Cell Applications and Cyfuse Biomedical K.K. announced the North American launch of a new 3D bioprinting technique to create 3D tissue from cells utilizing Cyfuse’s robotic Regenova 3D bioprinter. San Diego, Calif.-based Cell Applications said the launch will allow them to offer pay-for-service bio-printing to make scaffold-free tissue available for research use. “In addition to customized

Antibacterial coating may reduce medical implant infections

A common ingredient in sunscreen could be an effective antibacterial coating for medical implants such as joint replacements and pacemakers. Zinc oxide nanopyramids can disrupt methicillin-resistant Staphylococcus aureus (MRSA), reducing the film of bacteria growing on coated materials by over 95%. About one million implanted medical devices are infected each year. Treatment involves a long

Researchers create transplantation model for 3-D printed constructs

Using sugar, silicone and a 3-D printer, a team of bioengineers at Rice University and surgeons at the University of Pennsylvania have created an implant with an intricate network of blood vessels that points toward a future of growing replacement tissues and organs for transplantation. The research may provide a method to overcome one of