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7 companies in the race to make an artificial pancreas

March 31, 2017 By Fink Densford

Insulet: Competing with its own insulin control algorithm

Insulet is developing the Omnipod Horizon hybrid closed-loop system, and in February touted data from the 1st feasibility study of the device. Data from the trial indicated that the device’s insulin control algorithm met safety requirements and was able to perform well with minimal incidents of hypoglycemia.

The Billerica, Mass.–based company enrolled 24 patients with type 1 diabetes in the 36-hour study. The feasibility trial used a modified version of Insulet’s Omnipod, a Dexcom continuous glucose monitor and Insulet’s personalized model predictive control algorithm..

Use of the system was associated with significantly less time spent in hypoglycemic blood glucose range, Insulet reported, compared to ranges prior to the study. The study showed that patients hit the target blood glucose control range 69% of the time over the course of the 36 hours and maintained target blood glucose control 90% of the time overnight.

Last year, Insulet inked an initial deal with diabetes developer Mode Automated Glucose Control to develop an artificial pancreas using its flagship OmniPod device.

The deal put into motion the integration of the Mode AGC algorithm into the OmniPod glucose management system, the company said. The algorithm, co-developed by Insulet medical director Dr. Howard Zisser, Francis Doyle and Eval Dassau at UC Santa Barbara, is being studied in a feasibility trial using an OmniPod prototype and a Dexcom continuous glucose monitor.

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Comments

  1. Gayle Kirma says

    April 3, 2017 at 7:49 pm

    I’m patiently waiting for this to hit the marke; T1 for 58 years!

    Thank you!

    • Chris Newmarker says

      April 4, 2017 at 4:30 pm

      Thanks for the comment, Gayle. Hope you don’t have to wait much longer!

  2. James Dunlop says

    April 5, 2017 at 5:47 am

    but what about the advancements in this? worth looking at, it is being investigated by the same people that are investing in this product. hope for us T1 diabetics is coming, one way or another. there is hope.

    http://thejdca.org/practical-cure-project-update-bcg

  3. Erika Payne says

    April 5, 2017 at 12:43 pm

    Hats off to you, Gayle.

    Waiting impatiently.

    Mum of a 10-year-old T1

  4. Debbie says

    April 5, 2017 at 8:01 pm

    How do i get to be in the trial?

  5. Ronnie McBride says

    April 5, 2017 at 11:58 pm

    This will be great. I am 67 years old and am fighting the battle of diabetes. I would love to trial test something like this. I worked in the Medical field for 39 years and was always studying how to beat this terrible disease.

    Ronnie McBride

  6. James Culp says

    April 6, 2017 at 12:12 am

    I wish all success. I hope for biological approach to protect islet insulin producing cells for implant or infusion of cells to restore natural function of glucose metabolism. May God help us.

  7. Pat McAlister says

    June 3, 2017 at 4:59 pm

    T1D for 70 years. Why not a cure instead of costing us more and more to live. We are the support of these drug and device companies. Thank you for this article. I do a diabetic newsletter for a T1D optimist club. Our next speaker is building his own device.

    • Chris Newmarker says

      June 5, 2017 at 6:20 pm

      Thanks for the insights, Pat. I think it really says something about the motivation of the diabetes community that there’s so much do-it-yourself activity going on with devices, including when it comes to an artificial pancreas. Who do you have speaking?

  8. Frank van Olffen says

    May 12, 2018 at 10:06 pm

    You forgetting a big player in the Netherlands.

    https://inredadiabetic.nl

    • Chris Newmarker says

      May 16, 2018 at 4:33 pm

      Thanks for pointing out, Frank!

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