AxoGen, Inc. Announces Commercial Release And First Clinical Implant Of Avive Soft Tissue Membrane

AxoGen, Inc., a global leader in innovative surgical solutions for peripheral nerve injuries, today announced the commercial release and first clinical implant of Avive Soft Tissue Membrane.  Avive Soft Tissue Membrane is a minimally processed human umbilical cord membrane delivering the benefits of amnion to reduce inflammation and scar tissue formation. 

Avive represents AxoGen’s fourth surgical product and may be used in conjunction with nerve surgery techniques to proactively reduce inflammation and scarring.

“We are pleased to further expand our portfolio of products with the release of Avive Soft Tissue Membrane,” says Karen Zaderej, AxoGen’s President and Chief Executive Officer.  “Providing surgeons with a proactive solution to some of the common challenges they experience strengthens our position as the preeminent company in peripheral nerve surgery.”

Post-operative scar tissue and adhesion development is an inherent complication to nerve tissue following traumatic injury or surgical intervention. Used on injured nerves or surrounding soft tissues, Avive is a resorbable covering to keep potentially adherent surfaces apart. Processed from umbilical cord, Avive Soft Tissue Membrane is up to eight times thicker than amniotic sac membrane allowing for ideal handling, suturability, and performance. Avive is minimally processed to ensure preservation of the natural properties of umbilical cord amniotic membrane.  It stays in place during the critical phases of tissue regeneration to protect the tissue from inflammation and scarring. 

The first use of the Avive Soft Tissue Membrane was performed at The Buncke Clinic in San Francisco by Bauback Safa, MD, FACS, and Andrew Watt, MD. The implant was used in a revision of a crushed forearm. 

“Avive provides a novel solution to a challenging problem,” says Safa. “Following traumatic injury, we are often concerned with potential scarring, adhesions, and tethering of the nerve. Avive offers a material with the ability to reduce inflammation and scarring with handling properties that are ideal for applications in nerve surgery.”