Medical device innovation: Trudhesa
Impel PharmaceuticalsImpel Pharmaceuticals’ Trudhesa is a drug-device combination that delivers medication through the nose to treat migraines.
The Precision Olfactory Delivery (POD) device gently delivers medication nasal spray to provide the migraine headache pain relief medication Dihydroergotamine Mesylate in as few as 15 minutes with steady pain freedom for two days from one dose.
FDA approved the drug-device combination in September last year for the acute treatment of migraine with or without aura in adults. The nasal spray allows the medication to quickly absorb into the bloodstream through the vascular-rich upper nasal space. It bypasses the gut for rapid, sustained and consistent symptom relief without the need for an injection or infusion.