BiO2 Medical Granted CE Mark for the Angel Catheter, the First IVC Filter with a Prophylactic Use Indication

SAN ANTONIO/PRNewswire/ — BiO2 Medical, Inc.
a Texas based medical device manufacturer with corporate offices in San
Antonio, Texas, and R&D and manufacturing operations in Golden, Colorado,
announced today that it has received CE Mark approval for the Angel™ Catheter,
a Nitinol Inferior Vena Cava (IVC) filter, permanently attached to a central
venous catheter (CVC) for the use of preventing Pulmonary Embolism (PE) in
critically ill patients. This novel IVC filter/CVC combination device is the
first IVC filter with a prophylactic use indication, and allows attending
physicians the ability to place an IVC filter bedside in the Intensive Care
Unit (ICU), in a procedure resembling a routine CVC placement procedure.

According to Luis F. Angel, MD, BiO2 Medical’s Chief Medical
Officer and inventor of the Angel™ Catheter, “Obtaining the CE clearance
for commercialization of the Angel™ Catheter in Europe
is a significant step in our goal to provide an alternative for critically ill
patients at high risk of Pulmonary Embolism (PE). It also validates a long and
complex process of extensive testing for the use of our device as a
prophylaxis against PE.”

“With CE Mark approval for the Angel™ Catheter, and
preliminary safety data from a First in Man clinical study, these are exciting
times for the entire team at BiO2 Medical. We’ve been working diligently over
the past several years to bring this product to market, and I am justifiably
impressed and proud of everyone who has helped to bring this life saving device
to market,” stated Christopher E. Banas, BiO2 Medical’s Chairman and Chief
Executive Officer.

For more information regarding BiO2 Medical and the Angel™
Catheter, please visit www.bio2medical.com.