Medical Design and Outsourcing

  • Home
  • Medical Device Business
    • Mergers & Acquisitions
    • Financial
    • Regulatory
  • Applications
    • Cardiovascular
    • Devices
    • Imaging
    • Implantables
    • Medical Equipment
    • Orthopedic
    • Surgical
  • Technologies
    • Contract Manufacturing
    • Components
    • Electronics
    • Extrusions
    • Materials
    • Motion Control
    • Prototyping
    • Pumps
    • Tubing
  • Med Tech Resources
    • DeviceTalks Tuesdays
    • Digital Editions
    • eBooks
    • Manufacturer Search
    • Medical Device Handbook
    • MedTech 100 Index
    • Podcasts
    • Print Subscription
    • The Big 100
    • Webinars / Digital Events
    • Whitepapers
    • Video
  • 2022 Leadership in MedTech
    • 2022 Leadership Voting!
    • 2021 Winners
    • 2020 Winners
  • Women in Medtech

CLOTS 3 Study Delivers Lifesaving Results Using Covidien’s Blood Clot Prevention Technology

June 20, 2013 By Business Wire

Covidien (NYSE: COV), a leading global provider of healthcare products, has announced that an independent study conducted by the University of Edinburgh has successfully demonstrated the effectiveness of Covidien’s Kendall SCD™ system with Vascular Refill Detection Technology on immobile stroke patients.

The results of the CLOTS 3 trial were presented at the European Stroke Conference by Professor Martin S. Dennis of the University of Edinburgh’s Division of Clinical Neurosciences and also published in . The new study showed a 29.9% decrease in the development of proximal deep vein thrombosis (DVT) in immobile stroke patients who received intermittent pneumatic compression (IPC) using the Kendall SCD system with Vascular Refill Detection Technology, which delivers sequential, circumferential, gradient compression through thigh-length sleeves. Compared to the routine care group only, the IPC group also showed a 14% mortality risk reduction (p = 0.042) during the first six months after hospital admission for stroke.

“At last we have a simple, safe and affordable treatment that reduces the risk of DVT and even appears to reduce the risk of dying after a stroke,” said Prof. Dennis. “We estimate that this treatment could potentially help about 400,000 stroke patients each year in the U.S. If this number were treated, we would prevent about 20,000 patients from developing a DVT and perhaps save 10,000 lives.

“We believe that the national guidelines need to be revised in the light of our findings,” added Prof. Dennis. “The current guidelines have suggested that IPC should be considered only where blood thinning injections are unsuccessful or inappropriate, but this research suggests that IPC should be used in all patients at high risk of DVT.” “The results from the CLOTS 3 study are truly groundbreaking, “ said Mark A. Turco, MD, Chief Medical Officer, Vascular Therapies, Covidien. “The large, statistically significant mortality reduction in stroke patients treated with sequential compression versus routine care, as well as the near 30% reduction in proximal DVT, should revolutionize post-stroke treatment leading to improved patient outcomes.”

About the CLOTS 3 Trial
The largest trial of its kind, CLOTS 3 was a multicenter, randomized, controlled study that evaluated the effectiveness of IPC in reducing the risk of DVT and death in stroke patients. The study enrolled 2,876 patients between 2008 and 2012, and involved 105 hospitals in the United Kingdom. The trial was funded by the National Institute of Health, the Health Technology Assessment program and the Chief Scientist Office Scotland. Covidien donated the Kendall SCD compression systems to participating hospitals.

About Deep Vein Thrombosis and Intermittent Pneumatic Compression
DVTs are blood clots that can form in the leg, travel to the lungs and cause death. Current methods to prevent DVT include medicines that thin the blood. However, these medications often carry an increased risk of bleeding, which can be a serious drawback for stroke patients. Blood thinning agents have not been conclusively shown to reduce the risk of dying after stroke. IPC is a medical device that squeezes the leg gently to increase blood flow and is proven to decrease the risk of DVT. This is especially important in patients who are immobile, such as patients who suffer from acute stroke.

About Covidien
Covidien is a leading global healthcare products company that creates innovative medical solutions for better patient outcomes and delivers value through clinical leadership and excellence. Covidien manufactures, distributes and services a diverse range of industry-leading product lines in three segments: Medical Devices, Pharmaceuticals and Medical Supplies. With 2012 revenue of $11.9 billion, Covidien has 43,000 employees worldwide in 70 countries, and its products are sold in over 140 countries. Please visit www.covidien.com to learn more about our business.

Related Articles Read More >

Dexcom One
How Dexcom’s portfolio goes beyond highly-anticipated next-gen G7
A portrait of Stryker executive Siddarth Satish
How Stryker includes users for product design in the digital age
A Medtronic HVAD pump opened up to show the inner workings
Medtronic investigates HVAD pump welds after patient deaths
Galien Foundation 2022 nominees
18 of the world’s most innovative medical technologies

DeviceTalks Weekly.

May 13, 2022
Our Pre-Post-DeviceTalks Boston episode, also MedtronicTalks replay with Gastro CMO Austin Chiang
See More >

MDO Digital Edition

Digital Edition

Subscribe to Medical Design & Outsourcing. Bookmark, share and interact with the leading medical design engineering magazine today.

MEDTECH 100 INDEX

Medtech 100 logo
Market Summary > Current Price
The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing.
DeviceTalks

DeviceTalks is a conversation among medical technology leaders. It's events, podcasts, webinars and one-on-one exchanges of ideas & insights.

DeviceTalks

New MedTech Resource

Medical Tubing

Enewsletter Subscriptions

Enewsletter Subscriptions

MassDevice

Mass Device

The Medical Device Business Journal. MassDevice is the leading medical device news business journal telling the stories of the devices that save lives.

Visit Website
MDO ad
Medical Design and Outsourcing
  • MassDevice
  • DeviceTalks
  • MedTech 100 Index
  • Medical Tubing + Extrusion
  • Drug Delivery Business News
  • Drug Discovery & Development
  • Pharmaceutical Processing World
  • R&D World
  • About Us/Contact
  • Advertise With Us
  • Subscribe to Print Magazine
  • Subscribe to E-newsletter
  • Attend our Monthly Webinars
  • Listen to our Weekly Podcasts
  • Join our DeviceTalks Tuesdays Discussion

Copyright © 2022 WTWH Media, LLC. All Rights Reserved. Site Map | Privacy Policy | RSS

Search Medical Design & Outsourcing

  • Home
  • Medical Device Business
    • Mergers & Acquisitions
    • Financial
    • Regulatory
  • Applications
    • Cardiovascular
    • Devices
    • Imaging
    • Implantables
    • Medical Equipment
    • Orthopedic
    • Surgical
  • Technologies
    • Contract Manufacturing
    • Components
    • Electronics
    • Extrusions
    • Materials
    • Motion Control
    • Prototyping
    • Pumps
    • Tubing
  • Med Tech Resources
    • DeviceTalks Tuesdays
    • Digital Editions
    • eBooks
    • Manufacturer Search
    • Medical Device Handbook
    • MedTech 100 Index
    • Podcasts
    • Print Subscription
    • The Big 100
    • Webinars / Digital Events
    • Whitepapers
    • Video
  • 2022 Leadership in MedTech
    • 2022 Leadership Voting!
    • 2021 Winners
    • 2020 Winners
  • Women in Medtech