Medical Design and Outsourcing

  • Home
  • Medical Device Business
    • Mergers & Acquisitions
    • Financial
    • Regulatory
  • Applications
    • Cardiovascular
    • Devices
    • Imaging
    • Implantables
    • Medical Equipment
    • Orthopedic
    • Surgical
  • Technologies
    • Supplies and Components Index
    • Contract Manufacturing
    • Components
    • Electronics
    • Extrusions
    • Materials
    • Motion Control
    • Prototyping
    • Pumps
    • Tubing
  • MedTech Resources
    • Medtech Events in 2025
    • The 2024 Medtech Big 100
    • Medical Device Handbook
    • MedTech 100 Index
    • Subscribe to Print Magazine
    • DeviceTalks
    • Digital Editions
    • eBooks
    • Educational Assets
    • Manufacturer Search
    • Podcasts
    • Print Subscription
    • Webinars / Digital Events
    • Whitepapers
    • Voices
    • Video
  • 2025 Leadership
    • 2024 Winners
    • 2023 Winners
    • 2022 Winners
    • 2021 Winners
  • Women in Medtech
  • Advertise
  • Subscribe

electroCore’s bioelectric medicine, nVNS, successfully treats menstrual migraine

October 17, 2016 By Abigail Esposito

nVNS

A paper in the Journal of Headache and Pain found that electroCore’s nVNS, gammaCore, reduced menstrual and menstrual-related migraine attacks.

A paper in the Journal of Headache and Pain found that electroCore’s non-invasive vagus nerve stimulation treatment (nVNS), gammaCore, reduced menstrual and menstrual-related migraine attacks by more than a third, with 40% of the patients experiencing a reduction in migraine frequency of 50% or more.

Menstrual migraine/menstrual-related migraine is one the most common categories of migraine in women, and the most resistant to existing treatments. These migraines are also generally longer lasting, more debilitating and more prone to reoccurrence.

The open label study of 56 patients found that gammaCore therapy reduced the average number of migraine days by 35%, reduced the pain intensity of the migraines that did occur, and reduced the use of analgesics to acutely treat the migraine attacks by 37%.

“This is a significant result for the many millions of women who suffer from this particularly challenging form of migraine every month. The treatment, which the patient administers with gammaCore, is easy to use and has none of the usual side effects that many existing treatments cause,” said Professor Grazzi from the headache center at the Carlo Besta Neurological Institute in Milan Italy, who led the study.

A unique feature of gammaCore for women with menstrual-related migraine is the ability to use gammaCore for the week or two when the migraines most affect them without having to take a medication every day of the month.

“This is particularly important work in the field of headache. Most female migraineurs get menstrual-related migraine, and it’s usually their worst attack of the month. To complicate matters, many neurologists are uncomfortable addressing the hormonal triggers that underlie these attacks. This device offers a non-pharmacologic way to address women’s worst headaches,” said Dr. Anne Calhoun, Director of the Carolina Headache Center, and a co-author of the paper.

The study also found that there was a meaningful improvement in the quality of life for patients who responded. The authors postulate that the efficacy of the gammaCore treatment may be related to the suppression of excessive extracellular levels of glutamate through the trigeminal sensory pathways of women who are susceptible to estrogen-withdrawal attacks.

electroCore
electrocore.com

Related Articles Read More >

A photo of Capstan Medical's mitral valve implant, which uses nitinol.
Capstan Medical’s R&D head discusses the heart valve and robotics startup’s tech, engineering challenges and solutions, advice for others in medtech and how to join his team
An image of the Abbott Volt PFA System catheter and cart, which helps physicians visualize the location and effectiveness of cardiac ablation.
Abbott’s Volt PFA system isn’t just a catheter and a waveform
An image of Abbott's Infinity deep brain stimulation (DBS) implants and leads.
How Abbott developed the first-of-its-kind Infinity DBS system
An illustration showing the Edwards Lifesciences Sapien M3 transcatheter mitral valve replacement (TMVR) system's valve being placed in the heart. [Image courtesy of Edwards Lifesciences]
The top nitinol cardiac medtech news of 2025 (so far)
“mdo
EXPAND YOUR KNOWLEDGE AND STAY CONNECTED
Get the latest medical device business news, application and technology trends.

DeviceTalks Weekly

See More >

MDO Digital Edition

Digital Edition

Subscribe to Medical Design & Outsourcing. Bookmark, share and interact with the leading medical design engineering magazine today.

MEDTECH 100 INDEX

Medtech 100 logo
Market Summary > Current Price
The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing.
DeviceTalks

DeviceTalks is a conversation among medical technology leaders. It's events, podcasts, webinars and one-on-one exchanges of ideas & insights.

DeviceTalks

New MedTech Resource

Medical Tubing

MassDevice

Mass Device

The Medical Device Business Journal. MassDevice is the leading medical device news business journal telling the stories of the devices that save lives.

Visit Website
MDO ad
Medical Design and Outsourcing
  • MassDevice
  • DeviceTalks
  • MedTech100 Index
  • Medical Tubing + Extrusion
  • Medical Design Sourcing
  • Drug Delivery Business News
  • Drug Discovery & Development
  • Pharmaceutical Processing World
  • R&D World
  • About Us/Contact
  • Advertise With Us
  • Subscribe to Print Magazine
  • Subscribe to our E-Newsletter
  • Listen to our Weekly Podcasts
  • Join our DeviceTalks Tuesdays Discussion

Copyright © 2025 WTWH Media, LLC. All Rights Reserved. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media LLC. Site Map | Privacy Policy | RSS

Search Medical Design & Outsourcing

  • Home
  • Medical Device Business
    • Mergers & Acquisitions
    • Financial
    • Regulatory
  • Applications
    • Cardiovascular
    • Devices
    • Imaging
    • Implantables
    • Medical Equipment
    • Orthopedic
    • Surgical
  • Technologies
    • Supplies and Components Index
    • Contract Manufacturing
    • Components
    • Electronics
    • Extrusions
    • Materials
    • Motion Control
    • Prototyping
    • Pumps
    • Tubing
  • MedTech Resources
    • Medtech Events in 2025
    • The 2024 Medtech Big 100
    • Medical Device Handbook
    • MedTech 100 Index
    • Subscribe to Print Magazine
    • DeviceTalks
    • Digital Editions
    • eBooks
    • Educational Assets
    • Manufacturer Search
    • Podcasts
    • Print Subscription
    • Webinars / Digital Events
    • Whitepapers
    • Voices
    • Video
  • 2025 Leadership
    • 2024 Winners
    • 2023 Winners
    • 2022 Winners
    • 2021 Winners
  • Women in Medtech
  • Advertise
  • Subscribe