Epicenter selects five startups for ZeroTo510 medtech accelerator

Epicenter named five medtech startups to its 2025 ZeroTo510 Accelerator, a 13-week program in Memphis that helps early-stage founders prepare for commercialization.

The startups were chosen from applicants across 15 states. Each company will receive a $25,000 investment and training in areas such as business planning, regulatory strategy, reimbursement, quality, supply chain management and fundraising. The program will conclude with a Demo Day on Dec. 11 in Memphis.

“The medical device landscape is changing rapidly as new technologies emerge, and we’re really proud of the cohort we’ve put together this year that reflects many of those new breakthroughs,” said Olaf Schulz, director of the ZeroTo510 medtech programs at Epicenter. “These founders represent the future of healthcare innovation, and we’re excited to support them with our customized programming, resources, mentorship, and ecosystem that have helped our alumni companies thrive over the past decade.”

The 2025 cohort includes:

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  NatureFound Biotech describes ChitoSeal as “an innovative and resorbable guided bone regeneration membrane made from naturally occurring polymers.” [Photo courtesy of NatureFound Biotech]

  Dichotics Inc. (Memphis, Tennessee), which develops Audia Dichotics, a web-based platform to screen and treat auditory processing deficits in children and adults.
• Fluens Medical (Houston, Texas) is creating an implantable device to manage ascites, a complication of liver disease, by reinfusing fluid in a controlled way.
• NatureFound Biotech (Memphis, Tennessee) is commercializing ChitoSeal, a resorbable dental membrane for guided tissue regeneration in dental and reconstructive surgery.
• Navigator Medical (Memphis, Tennessee) has patented a needle guide to aid in forming buttonholes for vascular access during dialysis.
• Oya MedTech (Los Angeles, California) is developing underwear inserts and apparel that integrate skin health monitoring technology.

Since its founding, ZeroTo510 alumni have raised more than $104 million. The program is nationally recognized for its role in supporting medtech commercialization. It contributes to Memphis’ $4.1 billion medical device sector, which accounts for approximately 5.5% of the city’s GDP and supports more than 18,000 jobs, according to the Greater Memphis Medical Device Council.