Medical Design and Outsourcing

  • Home
  • Medical Device Business
    • Mergers & Acquisitions
    • Financial
    • Regulatory
  • Applications
    • Cardiovascular
    • Devices
    • Imaging
    • Implantables
    • Medical Equipment
    • Orthopedic
    • Surgical
  • Technologies
    • Contract Manufacturing
    • Components
    • Electronics
    • Extrusions
    • Materials
    • Motion Control
    • Prototyping
    • Pumps
    • Tubing
  • Med Tech Resources
    • DeviceTalks Tuesdays
    • Digital Editions
    • eBooks
    • Manufacturer Search
    • Medical Device Handbook
    • MedTech 100 Index
    • Podcasts
    • Print Subscription
    • The Big 100
    • Webinars / Digital Events
    • Whitepapers
    • Video
  • 2022 Leadership in MedTech
    • 2022 Leadership Voting!
    • 2021 Winners
    • 2020 Winners
  • Women in Medtech

Launch of First eUpdate Integrating Breakthroughs in ESMO Clinical Practice Guidelines

September 22, 2016 By European Society for Medical Oncology

ESMO, the leading European professional organization for medical oncology, launched today the first eUpdates for its world renowned ESMO Clinical Practice Guidelines (CPG)1.

eUpdates will be published on the ESMO website to provide CPG users with timely updates each time breakthrough necessitating rapid communication has occurred and when a Magnitude of Clinical Benefit Scale (MCBS)2 score has been produced for a new European Medicines Agency (EMA) therapy or a new indication.

The ESMO CPG on Cutaneous Melanoma3 is the first to benefit from eUpdates including the MCBS grading of the PD-1 checkpoint inhibitor nivolumab to reflect the rapidly growing body of evidence on the use of immunotherapy for this type of skin cancer and the recent approval of this therapy by the EMA. The second eUpdate for this CPG will provide practical diagnostic and treatment algorithms.

“eUpdates represent one of the most important innovations to the ESMO CPG,” said chair of the ESMO Clinical Practice Guidelines Committee4 George Pentheroudakis. “eUpdates will make the ESMO CPG an even more powerful and convenient tool for oncology professionals to remain up-to-date with the latest breakthroughs in oncology.”

The one page summary includes information on why an update was needed, recommendations for treatment, the ESMO MCBS scoring table, where applicable, as well as references. Elisabeth de Vries, chair of the ESMO Magnitude of Clinical Benefit Scale Working Group and a member of the ESMO Guidelines Steering Committee, adds, “This is an important step forward to provide rapid insight in the magnitude of benefit of newly registered drugs for physicians and their patients.” 

ESMO will produce an MCBS score for all new therapies approved after January 1, 2016 for patients with solid tumors in new or updated ESMO CPGs. “Thanks to the introduction of the eUpdates, even if a CPG is not due to be updated based on the regular development course, clinicians will be immediately alerted of the new EMA approved therapy with the related ESMO-MCBS score, including summary trial, efficacy and toxicity data,” added Pentheroudakis. “This information is highly significant in order to help both physicians and patients investigate therapeutic options and rationalize everyday clinic decisions, as well as health authorities in devising viable and equitable cancer care plans.”

In 2016, ESMO will release a total of 11 new and updated CPGs, with an improved format which includes standardized treatment management algorithms and flow-charts, personalized medicine synopsis tables and a MCBS scores for new therapies/indications approved by the EMA.

The first CPGs integrating an MCBS score for newly EMA approved indications will be published in a supplement to the October issue of Annals of Oncology5. Printed copies of the supplement containing updated CPG will be distributed from the ESMO booth during the ESMO 2016 Congress in October.
_________________________________________________________________

References:

1 Developed by groups of international experts who formulate recommendations based on evidence-based medicine with a multidisciplinary perspective on cancer treatment, ESMO CPG supports oncology professionals in their daily clinical decisions.  All ESMO CPGs are openly available on the ESMO website for the greater benefit of the oncology community. http://esmo.org/Guidelines

2 The ESMO Magnitude of Clinical Benefit Scale (ESMO-MCBS) is a standardized, generic, validated approach to stratify the magnitude of clinical benefit that can be anticipated from anti-cancer therapies. Developed by the European Society for Medical Oncology, this tool aims to assist oncology clinicians in evaluating the most effective anti-cancer medicines for their patients. The scale is applied to new anti-cancer drugs approved by the EMA after January 1, 2016. http://esmo.org/Policy/Magnitude-of-Clinical-Benefit-Scale
 
3 http://www.esmo.org/Guidelines/Melanoma/Cutaneous-Melanoma/eUpdate-Treatment-Recommendations
 
4 http://esmo.org/About-Us/Who-We-Are/Guidelines-Committee

5 http://annonc.oxfordjournals.org/content/27/suppl_5.toc (Available from 9/23/16)

(Credit: AlphaGalileo)

Related Articles Read More >

Biological Toolkit of Cells Assembled Like Legos
New Technology Keeps Eye On Babies’ Movement In The Womb
Robots Won’t Replace Teachers But Can Boost Children’s Education
Artificial Placenta Created In Laboratory

DeviceTalks Weekly.

May 13, 2022
Our Pre-Post-DeviceTalks Boston episode, also MedtronicTalks replay with Gastro CMO Austin Chiang
See More >

MDO Digital Edition

Digital Edition

Subscribe to Medical Design & Outsourcing. Bookmark, share and interact with the leading medical design engineering magazine today.

MEDTECH 100 INDEX

Medtech 100 logo
Market Summary > Current Price
The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing.
DeviceTalks

DeviceTalks is a conversation among medical technology leaders. It's events, podcasts, webinars and one-on-one exchanges of ideas & insights.

DeviceTalks

New MedTech Resource

Medical Tubing

Enewsletter Subscriptions

Enewsletter Subscriptions

MassDevice

Mass Device

The Medical Device Business Journal. MassDevice is the leading medical device news business journal telling the stories of the devices that save lives.

Visit Website
MDO ad
Medical Design and Outsourcing
  • MassDevice
  • DeviceTalks
  • MedTech 100 Index
  • Medical Tubing + Extrusion
  • Drug Delivery Business News
  • Drug Discovery & Development
  • Pharmaceutical Processing World
  • R&D World
  • About Us/Contact
  • Advertise With Us
  • Subscribe to Print Magazine
  • Subscribe to E-newsletter
  • Attend our Monthly Webinars
  • Listen to our Weekly Podcasts
  • Join our DeviceTalks Tuesdays Discussion

Copyright © 2022 WTWH Media, LLC. All Rights Reserved. Site Map | Privacy Policy | RSS

Search Medical Design & Outsourcing

  • Home
  • Medical Device Business
    • Mergers & Acquisitions
    • Financial
    • Regulatory
  • Applications
    • Cardiovascular
    • Devices
    • Imaging
    • Implantables
    • Medical Equipment
    • Orthopedic
    • Surgical
  • Technologies
    • Contract Manufacturing
    • Components
    • Electronics
    • Extrusions
    • Materials
    • Motion Control
    • Prototyping
    • Pumps
    • Tubing
  • Med Tech Resources
    • DeviceTalks Tuesdays
    • Digital Editions
    • eBooks
    • Manufacturer Search
    • Medical Device Handbook
    • MedTech 100 Index
    • Podcasts
    • Print Subscription
    • The Big 100
    • Webinars / Digital Events
    • Whitepapers
    • Video
  • 2022 Leadership in MedTech
    • 2022 Leadership Voting!
    • 2021 Winners
    • 2020 Winners
  • Women in Medtech