PancreaCell on Friday unveiled a patent pending combination micro regeneration stimulator and micro infusion pump designed to totally regenerate a failing pancreas and restore normal insulin production.
The PancreaCell micro stimulator uses precise bioelectric signaling to control release of 10 key organ regeneration proteins and signals for also controlling stem cell recruitment, proliferation and differentiation. The stimulator is complemented by an implantable, programmable, re-fillable micro infusion pump.
The micro pump is used to deliver PancreaCell’s proprietary PC-15 stem cell based regenerative cocktail once a week over a 36-month course of total organ regeneration treatment.
This proprietary composition includes a variety of modified cells including mesenchymal stem cells from bone marrow, umbilical cord derived cells, n eurogenin 3+ progenitor cells and adipose (fat) derived cells, a variety of growth factors including developmental morphogen proteins known as hedgehogs, islet homeostasis protein (IHoP), M2 macrophages, selected micro RNAs, BMP-7, PDLI, pancreatic derived matrix and nutrient hydrogel.
The therapy is complemented by delivery of auto-immune and anti-inflammatory agents such as highly purified Omega 3 fatty acids. The PancreaCell regeneration stimulator + micro pump device is implanted in a patient’s abdomen with a pacing infusion lead directed to the center of the pancreas fixated with a special soft tissue fixation tip. The re-filling silicon septum port for the micro pump is easily accessible for weekly re-fills of the PC-15 regenerative cocktail composition.
The company has designed a clinical protocol that it plans to launch later this year after pre-clinical safety studies have been completed.
PancreaCell, a Leonhardt Ventures Co., announced last month the filing of a provisional patent application for special bioelectric signals designed to stop cancer tumor growth by stopping cell division and blood supply which may be used to treat pancreatic cancer in a presumably less toxic way than chemo or radiation and with the benefit of a full regeneration program to follow eradication of the tumors.
