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New Study Explores Impact of More Uniform Distribution of Endovascular Coils in Cerebral Aneurysm Treatment

June 21, 2011 By Bio-Medicine.Org

RAYNHAM, Mass., June 21, 2011 /PRNewswire/ — A new study
published in the June edition of the Journal of NeuroInterventional
Surgery(1) highlights that a more uniform distribution of
endovascular coils may help in the treatment of cerebral aneurysms,
it was reported by Codman & Shurtleff, Inc. (Codman), a global
neurovascular and neuroscience company.  Codman’s
DELTAPAQ™ endovascular microcoils were used in the study.

Study authors found that the novel triangular primary wind
design of DELTAPAQ™ endovascular microcoils achieved a
tighter packing density and a more uniform distribution of the coil
mass across the aneurysm dome in comparison with helical and
complex endovascular microcoils.  DELTAPAQ coils were also
more likely to have the highest rate of angiographic occlusion.
 

Researchers concluded that the evaluation of emerging coil
technologies with respect to treatment durability may be well
served by an assessment of their uniformity of distribution within
an aneurysm, in addition to the traditional packing density and
angiographic occlusion scoring methods.  

“This study suggests that the uniformity across the dome of the
aneurysm may play an important role in enhancing the durability of
endovascular treatment and is an important area for further study
and confirmation,” said Bernard R. Bendok, MD, study co-author and
Associate Professor of Neurological Surgery and Radiology at
Northwestern University’s Feinberg School of Medicine.*  “The
application of a coil uniformity model may provide valuable design
information.”  

Study authors constructed silicone aneurysm models and devised
an assessment tool to objectively measure the coil uniformity
index, which when combined with the degree of angiographic
occlusion and packing density, can provide valuable information
regarding coil behavior.

In the in vitro study, DELTAPAQ coils were more uniformly
distributed in the dome of t

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SOURCE

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