Medical Design and Outsourcing

  • Home
  • Medical Device Business
    • Mergers & Acquisitions
    • Financial
    • Regulatory
  • Applications
    • Cardiovascular
    • Devices
    • Imaging
    • Implantables
    • Medical Equipment
    • Orthopedic
    • Surgical
  • Technologies
    • Contract Manufacturing
    • Components
    • Electronics
    • Extrusions
    • Materials
    • Motion Control
    • Prototyping
    • Pumps
    • Tubing
  • Med Tech Resources
    • DeviceTalks Tuesdays
    • Digital Editions
    • eBooks
    • Manufacturer Search
    • Medical Device Handbook
    • MedTech 100 Index
    • Podcasts
    • Print Subscription
    • The Big 100
    • Webinars / Digital Events
    • Whitepapers
    • Video
  • 2022 Leadership in MedTech
    • 2022 Leadership Voting!
    • 2021 Winners
    • 2020 Winners
  • Women in Medtech

Penn Medicine Researcher Receives $6 Million Grant for Cardiovascular Disease Study

January 3, 2011 By University of Pennsylvania

PHILADELPHIA – An international team of researchers led by Daniel J. Rader, MD, associate director of Penn Medicine’s Institute for Translational Medicine and Therapeutics, has received a $6 million grant from the Paris-based Fondation Leducq to study the molecular genetics of atherosclerotic cardiovascular disease. The team’s proposal, “Molecular Mechanisms of Novel Genes Associated with Plasma Lipids and Cardiovascular Disease,” was selected to receive the award through the Fondation’s Transatlantic Networks of Excellence Program.

  • Daniel J. Rader, MD (Click to view larger version.)

  • Gene for Cholesterol and Cardiovascular Disease Identified through Genome Scan
  • What Your Genes Say About You
  • Penn Preventive Cardiology Program
  • Penn Cardiovascular Institute: Lipids Research
  • University of Pennsylvania School of Medicine
  • University of Pennsylvania Health System

The investigation will focus on determining the molecular mechanisms of some of the most compelling genes to come out of genome-wide association studies (GWAS) for coronary heart disease and heart attack. Specifically, the research team will study six novel genes found by GWAS to be associated with heart disease in order to rigorously assess their function in physiological processes associated with cardiovascular disease and whether or not they are viable targets for future therapeutic developments.

The multidisciplinary, international research team includes experts in epidemiology, human genetics, molecular and cell biology, and animal physiology. In addition to identifying new potential therapeutic targets, this research program will also establish an infrastructure for the systematic evaluation of future GWAS results in the area of cardiovascular disease.

The award is funded through the Fondation Leducq’s Transatlantic Networks of Excellence Program. Each research network receives $6 million over five years to support a collaborative research program involving European and North American investigators.  In addition to Rader, other scientists involved in the study include:

  • European Coordinator: Christian Weber, MD, RWTH, Aachen University, Germany
  • Members: Endre Kiss-Toth, PhD, University of Sheffield, United Kingdom; Thomas Quertermous, MD, Stanford Cardiovascular Medicine, US; Sekar Kathiresan, MD,  Harvard Medical School and Massachusetts General Hospital, US; Mason Freeman, MD, Massachusetts General Hospital, US; Heiko Runz, MD, University of Heidelberg, Germany; Rainer Pepperkok, PhD, European Molecular Biology Laboratory, Germany; John Danesh, PhD, University of Cambridge, United Kingdom; Robert Hegele, MD, University of Western Ontario, Canada; Ronald Krauss, MD, University of California, Berkeley, US; Marju Orho-Melander, MD, Lund University, Sweden; and Ira Tabas, MD, PhD, Columbia University, US.

The Fondation Leducq, a Paris-based nonprofit institution, is dedicated to improving human health through international efforts to combat cardiovascular disease.

 

SOURCE

Related Articles Read More >

Dexcom One
How Dexcom’s portfolio goes beyond highly-anticipated next-gen G7
A portrait of Stryker executive Siddarth Satish
How Stryker includes users for product design in the digital age
A Medtronic HVAD pump opened up to show the inner workings
Medtronic investigates HVAD pump welds after patient deaths
Galien Foundation 2022 nominees
18 of the world’s most innovative medical technologies

DeviceTalks Weekly.

May 20, 2022
DeviceTalks Boston Post-Game – Editors’ Top Moments, Insulet’s Eric Benjamin on future of Omnipod 5
See More >

MDO Digital Edition

Digital Edition

Subscribe to Medical Design & Outsourcing. Bookmark, share and interact with the leading medical design engineering magazine today.

MEDTECH 100 INDEX

Medtech 100 logo
Market Summary > Current Price
The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing.
DeviceTalks

DeviceTalks is a conversation among medical technology leaders. It's events, podcasts, webinars and one-on-one exchanges of ideas & insights.

DeviceTalks

New MedTech Resource

Medical Tubing

Enewsletter Subscriptions

Enewsletter Subscriptions

MassDevice

Mass Device

The Medical Device Business Journal. MassDevice is the leading medical device news business journal telling the stories of the devices that save lives.

Visit Website
MDO ad
Medical Design and Outsourcing
  • MassDevice
  • DeviceTalks
  • MedTech 100 Index
  • Medical Tubing + Extrusion
  • Drug Delivery Business News
  • Drug Discovery & Development
  • Pharmaceutical Processing World
  • R&D World
  • About Us/Contact
  • Advertise With Us
  • Subscribe to Print Magazine
  • Subscribe to E-newsletter
  • Attend our Monthly Webinars
  • Listen to our Weekly Podcasts
  • Join our DeviceTalks Tuesdays Discussion

Copyright © 2022 WTWH Media, LLC. All Rights Reserved. Site Map | Privacy Policy | RSS

Search Medical Design & Outsourcing

  • Home
  • Medical Device Business
    • Mergers & Acquisitions
    • Financial
    • Regulatory
  • Applications
    • Cardiovascular
    • Devices
    • Imaging
    • Implantables
    • Medical Equipment
    • Orthopedic
    • Surgical
  • Technologies
    • Contract Manufacturing
    • Components
    • Electronics
    • Extrusions
    • Materials
    • Motion Control
    • Prototyping
    • Pumps
    • Tubing
  • Med Tech Resources
    • DeviceTalks Tuesdays
    • Digital Editions
    • eBooks
    • Manufacturer Search
    • Medical Device Handbook
    • MedTech 100 Index
    • Podcasts
    • Print Subscription
    • The Big 100
    • Webinars / Digital Events
    • Whitepapers
    • Video
  • 2022 Leadership in MedTech
    • 2022 Leadership Voting!
    • 2021 Winners
    • 2020 Winners
  • Women in Medtech