CAMBRIDGE,
Mass., Dec. 22, 2011 /PRNewswire/
— Quanterix Corporation, a company enabling a new generation of molecular
diagnostic tests based on its revolutionary Single Molecule Array (SiMoA™)
technology, has reported a method for detecting individual proteins within
microfabricated polymer arrays produced by Sony DADC. Quanterix recently
entered into a collaboration with Sony DADC for the development and manufacture
of “smart consumables” based on an optical disc format. This
method was published online in Lab on a Chip.
“We have developed a device that enables the fluidic
sealing and isolation of single molecules in arrays containing hundreds of
thousands of miniaturized wells. These consumables are manufactured using
high precision and high volume manufacturing processes, and will be at the
heart of the SiMoA instrument that we are currently developing. By using
arrays enclosed in microfluidic channels we are able to perform SiMoA in a
fully automated fashion,” said David Duffy, Ph.D., Vice President of
Research at Quanterix and corresponding author of the publication. “This
represents a significant milestone towards our goal of developing an automated platform
that enables single molecule sensitivity while offering significant advantages
for the manufacture of high quality, low-cost consumables. These devices
will facilitate high throughput and sensitive detection of biomarkers, and
address important applications in life science research and in vitro
diagnostics.”
Martin Madaus, Ph.D., Quanterix Chairman and CEO added,
“This achievement is an important step towards our goal to commercialize
the SiMoA technology. Working closely with our strategic partners,
Quanterix plans to develop and manufacture a fully automated instrument for its
SiMoA technology that will utilize these consumables to support a menu of
diagnostic tests. Quanterix expects to launch the life science instrument
in 2013, followed by an IVD platform to be commercialized in 2014.”
About Quanterix
Quanterix Corporation is developing its proprietary Single Molecule Array
(SiMoA™) technology for the in vitro diagnostics and life science research
markets. The digital nature of SiMoA yields unprecedented assay performance,
stemming from a 1,000-fold improvement in sensitivity compared with today’s
analog only technology. SiMoA will enable researchers in life science to
validate novel, low abundance biomolecules from a single droplet of blood,
leading to greater insight into disease detection, diagnosis, therapy selection
and disease monitoring. Automated systems based on SiMoA will provide
diagnostic test information to healthcare practitioners faster, with greater
reliability, unprecedented range and increased cost effectiveness.
Founded in 2007, the privately held Cambridge, Massachusetts-based company is
backed by leading life science investors including ARCH Venture Partners, Bain
Capital Ventures, and Flagship Ventures. For additional information, please
visit www.quanterix.com.
Posted by Sean Fenske, Editor-in-Chief, MDT