STOCKHOLM–(BUSINESS
WIRE)–Regulatory News: RaySearch Laboratories AB announces that version
2.5 of RaySearchs RayStation® treatment planning system has been released for
clinical use in Europe and USA and is pending regulatory approval in Canada.
The new version includes a wide range of new features and improvements.

RayStation® 2.5 includes all of RaySearchs market-leading
optimization algorithms for VMAT, IMRT and 3D-CRT alongside a comprehensive set
of tools for traditional 3D-CRT planning. This means that the system can be
used clinically for treatment planning of all various treatment modalities of
photon therapy. RayStation® 2.5 also has full support for combining all of
these techniques in the same treatment. In addition, the new version includes
improvements of RaySearchs unique multi-criteria optimization (MCO) solution
for IMRT. This highly intuitive tool lets the clinician evaluate the impact of
changing different treatment priorities in real-time, which has a large
potential to speed up the time-consuming treatment planning optimization
process. The MCO solution has been developed in collaboration with Massachusetts General Hospital
in Boston, USA.

From the start, RayStation® was designed to handle 4D
adaptive radiation therapy and the new release includes groundbreaking features
in this field. Using advanced deformable registration algorithms, RayStation®
2.5 allows the users to perform dose tracking. This offers the possibility to
perform accurate dose accumulation of any delivered or planned dose to any
patient geometry using any combination of CT, MR, PET and 4D-CT data sets.
RayStation® is the first treatment planning system that lets the clinicians
monitor the impact of a changing patient geometry as the treatment progresses,
and seamlessly adjust the treatment in the same system. The dose tracking
functionality has been developed in collaboration with Princess
Margaret Hospital
in Toronto, Canada
and is available for installation in Europe but is pending regulatory clearance
in USA and Canada.

In addition to the new features, RayStation® 2.5 includes
major improvements and performance enhancements that further facilitate and
speed up the treatment planning process. For example, the collapsed cone
clinical dose engine has been reimplemented, now offering unmatched speed, and
the DICOM communication capabilities have been further improved. Examples in
the usability area include extensive use of templates throughout the system,
unlimited undo functionality and all sorts of keyboard shortcuts that are
expected in modern software.

“We are very proud that we now can offer the first complete
version of RayStation®. The system is now ready to be the workhorse for all
photon treatments for all types of clinics, from smaller ones to large
university hospitals with very advanced needs”, says Johan Löf, CEO of
RaySearch.

“We have a long-standing reputation of excellence in the
field of optimization and firmly believe that we have now taken the lead in the
field of adaptive therapy as well. I am convinced that the combination of optimization
and adaptation is the future of radiation therapy and we fully intend to stay
in the forefront of this development. We will continue to work closely with our
customers and research partners to build new features and refine the system at
a very high pace”, concludes Johan Löf.

About RayStation®

RayStation® integrates all RaySearchs advanced treatment planning solutions
into a flexible treatment planning system. It combines unique features such as
multi-criteria optimization tools with full support for 4D adaptive radiation
therapy. It also includes functionality such as RaySearchs market-leading
algorithms for IMRT and VMAT optimization and highly accurate dose engines for
both photon and proton therapy. The system is built on the latest software
architecture and has a graphical user interface offering state-of-the-art
usability.

About RaySearch

RaySearch Laboratories is a medical technology company that develops advanced
software solutions for improved radiation therapy of cancer. RaySearchs
products are mainly sold through license agreements with leading partners such
as Philips, Nucletron, IBA Dosimetry, Varian, Accuray and Siemens. To date, 15
products have been launched through partners and RaySearchs software is used
at some 1,800 clinics in more than 30 countries. In addition, RaySearch offers
the proprietary treatment planning system RayStation® directly to clinics.
RaySearch was founded in 2000 as a spin-off from Karolinska Institutet in Stockholm and the company
is listed in the Small Cap segment on NASDAQ OMX Stockholm.

For more information about RaySearch, visit www.raysearchlabs.com.

Posted by Sean Fenske, Editor-in-Chief, MDT