Medical Design and Outsourcing

  • Home
  • Medical Device Business
    • Mergers & Acquisitions
    • Financial
    • Regulatory
  • Applications
    • Cardiovascular
    • Devices
    • Imaging
    • Implantables
    • Medical Equipment
    • Orthopedic
    • Surgical
  • Technologies
    • Contract Manufacturing
    • Components
    • Electronics
    • Extrusions
    • Materials
    • Motion Control
    • Prototyping
    • Pumps
    • Tubing
  • Med Tech Resources
    • DeviceTalks Tuesdays
    • Digital Editions
    • eBooks
    • Manufacturer Search
    • Medical Device Handbook
    • MedTech 100 Index
    • Podcasts
    • Print Subscription
    • The Big 100
    • Webinars / Digital Events
    • Whitepapers
    • Video
  • 2022 Leadership in MedTech
    • 2022 Leadership Voting!
    • 2021 Winners
    • 2020 Winners
  • Women in Medtech

Renal Denervation May Reduce Hypertension in Patients with Renal Artery Stents

April 30, 2014 By Journal of Endovascular Therapy

Journal of Endovascular Therapy: Patients with hypertension after renal artery stenting who do not respond to drug treatment may have another option. Renal sympathetic denervation can help lower blood pressure by desensitizing nerve endings in the vascular wall. However, recent studies of this treatment concept have excluded patients with stented renal arteries.

The Journal of Endovascular Therapy presents a proof-of-concept study of 10 patients with renal artery stents who were treated with radiofrequency renal denervation. The study examined office blood pressure and ambulatory blood pressure measurements, medication, and renal assessment at baseline and at 3, 6, and 12 months following the procedure.

In this procedure, a catheter is inserted into the arteries leading to the kidney, and radiofrequency energy is dispensed to a segment of the artery, keeping a safe distance of 5 mm from the stented segments. Once the nerve endings are desensitized, the renal sympathetic activity is reduced and decreased blood pressure can result.

Current international guidelines, however, exclude patients with an artery stent because of concern that application of radiofrequency through a metallic stent might induce restenosis or occlusion. Alternate technologies for producing denervation, such as ultrasound, brachytherapy, and local drug delivery, are also under clinical investigation.

In this study, a successful response to treatment was considered a reduction of at least 10 mm Hg in office blood pressure as well as renal artery patency. Nine of the 10 patients met this goal. The patients showed sustained decreased readings in office blood pressure from baseline to 3, 6, and 12 months. Initial readings averaging about 190/84 mm Hg declined to 158/76 mm Hg after 12 months. No renal artery restenosis or aneurysm had occurred at 1 year.

While this article makes a case for the expansion of renal denervation studies to include patients with stents, an accompanying commentary points to other trials of this procedure that have not met with the same success. This issue of the journal also includes a case study outlining complications. Also noted are the recently released 6-month results of the SYMPLICITY HTN-3 trial comparing renal denervation against a sham procedure. The results show no significant differences between the two approaches. The commentary urges a case-by-case consideration for renal denervation while further research is conducted.

Full text of the article, “Renal Denervation for Hypertension Refractory to Renal Artery Stenting” and commentary article, Journal of Endovascular Therapy, Vol. 21, No. 2, 2014, are now available.

Related Articles Read More >

Johnson & Johnson Office of Digital Innovation Leader Peter Schulam
Imagining the future of cloud-connected medical devices with Johnson & Johnson leaders
Withings Body Scan
Withings plans launch for Body Scan smart scale platform
BinaxNow COVID-19 Ag Card
Time recognizes Abbott offerings among this year’s 100 best inventions
Koya Medical’s Dayspring device
Koya Medical reports positive early results in Dayspring lymphedema trial

DeviceTalks Weekly.

May 13, 2022
Our Pre-Post-DeviceTalks Boston episode, also MedtronicTalks replay with Gastro CMO Austin Chiang
See More >

MDO Digital Edition

Digital Edition

Subscribe to Medical Design & Outsourcing. Bookmark, share and interact with the leading medical design engineering magazine today.

MEDTECH 100 INDEX

Medtech 100 logo
Market Summary > Current Price
The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing.
DeviceTalks

DeviceTalks is a conversation among medical technology leaders. It's events, podcasts, webinars and one-on-one exchanges of ideas & insights.

DeviceTalks

New MedTech Resource

Medical Tubing

Enewsletter Subscriptions

Enewsletter Subscriptions

MassDevice

Mass Device

The Medical Device Business Journal. MassDevice is the leading medical device news business journal telling the stories of the devices that save lives.

Visit Website
MDO ad
Medical Design and Outsourcing
  • MassDevice
  • DeviceTalks
  • MedTech 100 Index
  • Medical Tubing + Extrusion
  • Drug Delivery Business News
  • Drug Discovery & Development
  • Pharmaceutical Processing World
  • R&D World
  • About Us/Contact
  • Advertise With Us
  • Subscribe to Print Magazine
  • Subscribe to E-newsletter
  • Attend our Monthly Webinars
  • Listen to our Weekly Podcasts
  • Join our DeviceTalks Tuesdays Discussion

Copyright © 2022 WTWH Media, LLC. All Rights Reserved. Site Map | Privacy Policy | RSS

Search Medical Design & Outsourcing

  • Home
  • Medical Device Business
    • Mergers & Acquisitions
    • Financial
    • Regulatory
  • Applications
    • Cardiovascular
    • Devices
    • Imaging
    • Implantables
    • Medical Equipment
    • Orthopedic
    • Surgical
  • Technologies
    • Contract Manufacturing
    • Components
    • Electronics
    • Extrusions
    • Materials
    • Motion Control
    • Prototyping
    • Pumps
    • Tubing
  • Med Tech Resources
    • DeviceTalks Tuesdays
    • Digital Editions
    • eBooks
    • Manufacturer Search
    • Medical Device Handbook
    • MedTech 100 Index
    • Podcasts
    • Print Subscription
    • The Big 100
    • Webinars / Digital Events
    • Whitepapers
    • Video
  • 2022 Leadership in MedTech
    • 2022 Leadership Voting!
    • 2021 Winners
    • 2020 Winners
  • Women in Medtech