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Reportlinker Adds Proteomics – Technologies, Markets and Companies

March 7, 2011 By Bio-Medicine.Org

NEW YORK, March 7, 2011 /PRNewswire/ — Reportlinker.com
announces that a new market research report is available in its
catalogue:

Proteomics – Technologies, Markets and Companies

http://www.reportlinker.com/p0203550/Proteomics—Technologies-Markets-and-Companies.html

Summary

This report describes and evaluates the proteomic technologies
that will play an important role in drug discovery, molecular
diagnostics and practice of medicine in the post-genomic era – the
first decade of the 21st century. Most commonly used technologies
are 2D gel electrophoresis for protein separation and analysis of
proteins by mass spectrometry. Microanalytical protein
characterization with multidimentional liquid chromatography/mass
spectrometry improves the throughput and reliability of peptide
mapping. Matrix-Assisted Laser Desorption Mass Spectrometry
(MALDI-MS) has become a widely used method for determination of
biomolecules including peptides, proteins. Functional proteomics
technologies include yeast two-hybrid system for studying protein-
protein interactions. Establishing a proteomics platform in the
industrial setting initially requires implementation of a series of
robotic systems to allow a high-throughput approach for analysis
and identification of differences observed on 2D electrophoresis
gels. Protein chips are also proving to be useful. Proteomic
technologies are now being integrated into the drug discovery
process as complimentary to genomic approaches. Toxicoproteomics,
i.e. the evaluation of protein expression for understanding of
toxic events, is an important application of proteomics in
preclinical drug safety. Use of bioinformatics is essential for
analy

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SOURCE

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