Medical Design and Outsourcing

  • Home
  • Medical Device Business
    • Mergers & Acquisitions
    • Financial
    • Regulatory
  • Applications
    • Cardiovascular
    • Devices
    • Imaging
    • Implantables
    • Medical Equipment
    • Orthopedic
    • Surgical
  • Technologies
    • Supplies and Components Index
    • Contract Manufacturing
    • Components
    • Electronics
    • Extrusions
    • Materials
    • Motion Control
    • Prototyping
    • Pumps
    • Tubing
  • MedTech Resources
    • Medtech Events in 2025
    • The 2024 Medtech Big 100
    • Medical Device Handbook
    • MedTech 100 Index
    • Subscribe to Print Magazine
    • DeviceTalks
    • Digital Editions
    • eBooks
    • Manufacturer Search
    • Podcasts
    • Print Subscription
    • Webinars / Digital Events
    • Whitepapers
    • Voices
    • Video
  • 2025 Leadership
    • 2024 Winners
    • 2023 Winners
    • 2022 Winners
    • 2021 Winners
  • Women in Medtech
  • Advertise
  • Subscribe

Software Pushes Osteoarthritis Diagnosis Ahead

March 29, 2016 By UNIVERSITY OF EASTERN FINLAND

Published in Nature, a recent study from the University of Eastern Finland developed and validated a novel computational modelling method for the assessment of the patient-specific progression of osteoarthritis in the knee joint by using MRI data. The research group comprises researchers from the University of Eastern Finland and Lund University.

“The method we have developed is based on stresses experienced by the knee joint during walking, and these were simulated on a computer. Our idea was that walking-induced cumulative stresses that exceed a certain threshold will cause local degeneration in the articular cartilage of the knee,” says Postdoctoral Researcher Mika Mononen from the University of Eastern Finland’s Department of Applied Physics.

The patient-specific estimates of the progression of osteoarthritis obtained by computer modelling were validated against four-year follow-up data from X-ray measurements, in which the thickness of the articular cartilage in the knee was evaluated by using the Kellgren-Lawrence method. For the validation of the model, two patient groups were established: the normal weight group and the overweight group.

In the normal weight group, the thickness of healthy cartilage did not change over the four-year follow-up, whereas significant degeneration was observed in the overweight group. “The study shows that this new method, which is based on computer modelling, was able to predict similar changes in the articular cartilage of the knee as experimental follow-up data,” Mononen says.

In the future, the method can serve as a new tool for making patient-specific prognoses on the progression of osteoarthritis. Furthermore, the method can be used for assessing the patient-specific effects of overweight on the future health of the knee joint as well as the success of clinical treatment such as menisectomy, a widely used surgical procedure.

Related Articles Read More >

A photo showing the Dualto Energy System's modular design with two generators stacked for two users at a time.
What J&J MedTech’s new Dualto says about the OR of the future — and Ottava
An illustration showing the Edwards Lifesciences Sapien M3 transcatheter mitral valve replacement (TMVR) system's valve being placed in the heart. [Image courtesy of Edwards Lifesciences]
Q&A with Darshin Patel, who led the Edwards Lifesciences Sapien M3 TMVR system’s development
A photo of nitinol, a nickel-titanium alloy used for medical devices such as stents, heart valves, catheters and orthopedics.
What is nitinol and where is it used?
An illustration showing the The Focal One Robotic HIFU system ablating a tumor with ultrasound energy.
Cleveland Clinic reports world’s first transcontinental robot-assisted focal therapy procedure for prostate cancer
“mdo
EXPAND YOUR KNOWLEDGE AND STAY CONNECTED
Get the latest medical device business news, application and technology trends.

DeviceTalks Weekly

See More >

MDO Digital Edition

Digital Edition

Subscribe to Medical Design & Outsourcing. Bookmark, share and interact with the leading medical design engineering magazine today.

MEDTECH 100 INDEX

Medtech 100 logo
Market Summary > Current Price
The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing.
DeviceTalks

DeviceTalks is a conversation among medical technology leaders. It's events, podcasts, webinars and one-on-one exchanges of ideas & insights.

DeviceTalks

New MedTech Resource

Medical Tubing

MassDevice

Mass Device

The Medical Device Business Journal. MassDevice is the leading medical device news business journal telling the stories of the devices that save lives.

Visit Website
MDO ad
Medical Design and Outsourcing
  • MassDevice
  • DeviceTalks
  • MedTech100 Index
  • Medical Tubing + Extrusion
  • Medical Design Sourcing
  • Drug Delivery Business News
  • Drug Discovery & Development
  • Pharmaceutical Processing World
  • R&D World
  • About Us/Contact
  • Advertise With Us
  • Subscribe to Print Magazine
  • Subscribe to our E-Newsletter
  • Listen to our Weekly Podcasts
  • Join our DeviceTalks Tuesdays Discussion

Copyright © 2025 WTWH Media, LLC. All Rights Reserved. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media LLC. Site Map | Privacy Policy | RSS

Search Medical Design & Outsourcing

  • Home
  • Medical Device Business
    • Mergers & Acquisitions
    • Financial
    • Regulatory
  • Applications
    • Cardiovascular
    • Devices
    • Imaging
    • Implantables
    • Medical Equipment
    • Orthopedic
    • Surgical
  • Technologies
    • Supplies and Components Index
    • Contract Manufacturing
    • Components
    • Electronics
    • Extrusions
    • Materials
    • Motion Control
    • Prototyping
    • Pumps
    • Tubing
  • MedTech Resources
    • Medtech Events in 2025
    • The 2024 Medtech Big 100
    • Medical Device Handbook
    • MedTech 100 Index
    • Subscribe to Print Magazine
    • DeviceTalks
    • Digital Editions
    • eBooks
    • Manufacturer Search
    • Podcasts
    • Print Subscription
    • Webinars / Digital Events
    • Whitepapers
    • Voices
    • Video
  • 2025 Leadership
    • 2024 Winners
    • 2023 Winners
    • 2022 Winners
    • 2021 Winners
  • Women in Medtech
  • Advertise
  • Subscribe