MEQUON, Wis.–(BUSINESS
WIRE)–Titan Spine, a medical device surface technology company focused on
the development of innovative spinal interbody fusion implants, announced today
that an article published in The Spine Journal reports in-vitro data that
demonstrates a superior bone-forming response to the company’s unique titanium
implant surface when compared to smooth titanium and Polyetheretherketone
(PEEK). In particular, the peer-reviewed data shows that Titan Spine’s surface,
which features a proprietary, patent-protected combination of textures on the
macro, micro, and nano levels, significantly increased osteoblast maturation
and local production of bone morphogenetic proteins (BMP’s). The authors, led
by Barbara Boyan, Ph.D., Professor of Biomedical Engineering at the Institute
for Bioengineering and Bioscience, Georgia Institute of Technology, conclude
that “modifying surface structure is sufficient to create an osteogenic
environment that could enhance bone formation and implant stability, without
addition of exogenous growth factors.”
“We are very pleased that this data set has been published,”
commented Kevin Gemas, President of Titan Spine. “It clearly illustrates that
our surface technology produces a superior environment for bone production over
other common interbody fusion implant materials. This data, and others we hope
will be published in the future, is helping to change the way spine surgeons
and the rest of the spinal community think about interbody fusion implants. No
longer should they be thought of as mere interbody spacers, but rather as
active participants in the fusion process that promote the body to produce
BMP’s naturally and avoid the need for the addition of BMP that was developed
externally.”
The abstract of the article, titled, “Osteoblasts exhibit a
more differentiated phenotype and increased bone morphogenetic protein
production on titanium alloy substrates than on poly-ether-ether-ketone,” can
be viewed at http://www.thespinejournalonline.com/article/S1529-9430(12)00091-5/abstract.
About the Company – Titan Spine, LLC is a privately-owned
medical implant surface technology company in Mequon, Wisconsin
that is focused on the design and manufacturing of proprietary interbody fusion
devices for the spine. The company is committed to advancing the science of
surface engineering to enhance the treatment of various pathologies of the
spine that require fusion. Visit www.titanspine.com to learn more and to view an animation
that depicts the cellular response to the company’s surface technology.