A hydrogel material embedded with a protein to improve blood vessel growth may boost the success rate of transplanting insulin-producing islet cells into patients with Type I diabetes, according to a preclinical study published in the journal Science Advances.
In the newly-published work, supported by the National Institutes of Health and the Juvenile Diabetes Research Foundation, the combination improved the survival rate of transplanted insulin-producing cells.
The technology could help people with diabetes or those who have had their pancreas removed due to severe pancreatitis. The team of researchers used the hydrogel material and protein combo to evaluate multiple sites for islet cell cluster implantation.
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