Even as the world’s largest medical device companies grapple with COVID-19 and the resulting recession, they’re doing important work to help humanity manage the crisis.

Read on to find out more about the 10 largest companies in the Big 100, MassDevice and Medical Design & Outsourcing‘s annual analysis of the worlds’ 100 largest medical device companies.

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The Big 100 is a team effort. Senior editor Danielle Kirsh compiles the data — examining companies’ annual reports early each year, as soon as the prior year’s financials begin to trickle in. We compile the listings and rank the companies according to annual revenues, then R&D spending and number of employees. Once the numbers are collected, we attempt to contact each of the 100 companies to confirm our findings.

Executive editor Chris Newmarker and assistant editor Sean Whooley wrote the company profiles.