The Omnigraft dermal regeneration matrix from Integra Lifesciences is an advanced bilayer dermal regeneration matrix that treats diabetic foot ulcers. It is the only FDA-approved product that can regenerate native dermal tissue, according to the company. The patch has a built-in silicone layer that serves as a temporary epidermal layer and provides immediate coverage for wound protection. It can be removed between two and three weeks. Under the silicone layer is a collagen/chrondroitin-6-sulfate matrix that acts as a dermal replacement layer. It is a bioengineered scaffold that promotes dermal regeneration and is designed with a controlled porosity and degradation rate.The Omnigraft dermal regeneration matrix is designed to be used for treating partial and full thickness neuropathic diabetic foot ulcers that are more than six weeks old with no capsule, tendon or bone showing.