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New Data Demonstrates Victoza® (liraglutide rDNA injection) Provided Superior and Sustained Blood Sugar Control and Weight Reduction Compared to Januvia® (sitagliptin) at On…

June 28, 2010 By Bio-Medicine.Org

ORLANDO, Fla., June 28 /PRNewswire/ — Poster 16LB —
Late-breaking Novo Nordisk (NVO) extension data presented today at
the 70th Annual Scientific Sessions of the American Diabetes
Association (ADA) showed that once-daily Victoza® in
combination with metformin produced sustained and significantly
greater reductions in A1c, body weight and fasting plasma glucose
(FPG) than Januvia® plus metformin at 52 weeks.

Key findings from the study include:

  • Patients treated with 1.2 mg and 1.8 mg of
    Victoza® experienced greater reductions in A1c than
    those treated with Januvia® 100 mg (-1.3% and -1.5%
    versus -0.9%)
  • Victoza® provided greater weight loss versus
    patients treated with Januvia® (2.8 kg [6.16 lbs] and 3.7 kg [8.14 lbs] for 1.2 mg and 1.8 mg respectively, 1.2 kg
    [2.64 lbs] for Januvia®)
  • Victoza® provided greater change from
    baseline FPG readings than those treated with
    Januvia® (-1.7 mmol/L and -2.0 mmol/L for 1.2 mg and
    1.8 mg respectively, versus -0.6 mmol/L)
  • Patients treated with Victoza® 1.8 mg reported
    significantly greater treatment satisfaction than those treated
    with Januvia®

“What is so encouraging about these data is that
Victoza® at both doses was more effective than
Januvia® at achieving blood sugar control in people
with type 2 diabetes over a period of one year.  Patients who
began the trial with higher A1c levels achieved greater reductions
in A1c with treatment with Victoza®,” said Dr. Richard Pratley, of the Diabetes and
Metabolism Tr

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SOURCE

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