Medical Design and Outsourcing

  • Home
  • Medical Device Business
    • Mergers & Acquisitions
    • Financial
    • Regulatory
  • Applications
    • Cardiovascular
    • Devices
    • Imaging
    • Implantables
    • Medical Equipment
    • Orthopedic
    • Surgical
  • Technologies
    • Supplies and Components Index
    • Contract Manufacturing
    • Components
    • Electronics
    • Extrusions
    • Materials
    • Motion Control
    • Prototyping
    • Pumps
    • Tubing
  • MedTech Resources
    • Medtech Events in 2025
    • The 2024 Medtech Big 100
    • Medical Device Handbook
    • MedTech 100 Index
    • Subscribe to Print Magazine
    • DeviceTalks
    • Digital Editions
    • eBooks
    • Educational Assets
    • Manufacturer Search
    • Podcasts
    • Print Subscription
    • Webinars / Digital Events
    • Whitepapers
    • Voices
    • Views
    • Video
  • 2025 Leadership
    • 2024 Winners
    • 2023 Winners
    • 2022 Winners
    • 2021 Winners
  • Women in Medtech
  • Advertise
  • Subscribe

Study Published in European Radiology Further Supports the Use of Hologic’s Breast Tomosynthesis in Cancer Screening in Practices Using Double Reads

April 16, 2013 By PR Newswire

BEDFORD, Mass., April 16, 2013 /PRNewswire/ — Hologic, Inc. (Hologic or the Company) (NASDAQ: HOLX), a leading developer, manufacturer and supplier of premium diagnostics, medical imaging systems and surgical products dedicated to serving the healthcare needs of women, today announced that a new study published online in advance of print by European Radiology supports the use of breast tomosynthesis in combination with 2-dimensional (2D) imaging in breast cancer screening programs using independent double reading with arbitration.

The study, “Prospective Trial Comparing Full-field Digital Mammography (FFDM) versus Combined FFDM and Tomosynthesis in a Population-based Screening Programme Using Independent Double Reading with Arbitration,” was led by Per Skaane, M.D., Ph.D. of Oslo University Hospital Ullevaal. [1] The analysis included a total of 12,621 screening examinations of women participating in the Oslo Tomosynthesis Screening Trial. In double reading, two radiologists independently read the same case and if the radiologists disagree on the diagnosis, there is an arbitration or consensus meeting where the final diagnosis of the case is decided. Double reading has been shown to increase cancer detection and is the standard method used for interpretation of mammograms for most countries outside of the U.S. with organized population-based screening programs. This study compares double reading of 2D mammography with double reading of 2D mammography plus tomosynthesis.

The researchers used Hologic’s breast tomosynthesis cancer screening technology and found:

  • Tomosynthesis-based screening was successfully implemented in a large prospective screening trial. 
  • Double reading of tomosynthesis-based examinations significantly reduced false-positive interpretations. False-positive interpretations were decreased by 18% using 2D plus tomosynthesis.
  • Double reading of tomosynthesis-based examinations significantly increased the detection of breast cancers by approximately 30%. The detection of invasive cancers was increased by approximately 40%.

“It is very encouraging, though not surprising, to see confirmation of the strong benefits our tomosynthesis technology can bring to users across different clinical environments,” said Peter Soltani , Hologic’s Senior Vice President and General Manager of Breast Health. “The Oslo data clearly indicates that double reading of 2D plus tomosynthesis imaging results in a large increase in the detection of invasive cancers and a reduction in false positives when compared with 2D double readings alone. This study reinforces a previous study measuring the benefits of tomosynthesis for a single reader and demonstrates that tomosynthesis provides major improvements in breast cancer screening for both single and double-reading screening methods. We believe that Hologic’s breast tomosynthesis technology can make significant inroads in overcoming the limitations of conventional mammography, namely missed cancers and unnecessary recalls, and we expect the results of this study to further support the adoption of our tomosynthesis technology.”

The European Radiology paper is the first peer-reviewed publication comparing the performance of double reading of 2D exams with double reading of 2D plus tomosynthesis imaging in a large prospective clinical trial.

Hologic’s breast tomosynthesis technology has been approved for use for breast cancer screening and diagnosis in countries recognizing the CE mark since 2008. It was approved for use in the U.S. in February, 2011. Hologic systems are now in use in 48 states in the U.S. and over 50 countries.

For more information about Hologic’s breast tomosynthesis technology, please visit www.BreastTomo.com (for healthcare providers) and www.Hologic3D.com (for patients).

About Hologic, Inc.

Hologic, Inc. is a leading developer, manufacturer and supplier of premium diagnostic products, medical imaging systems, and surgical products. The Company operates four core business units focused on diagnostics, breast health, GYN surgical and skeletal health. With a comprehensive suite of technologies and a robust research and development program, Hologic is committed to improving lives. The Company is headquartered in Massachusetts.

Hologic is a trademark and/or registered trademark of Hologic, Inc., and/or its subsidiaries in the United States and/or other countries.

Related Articles Read More >

An illustration of Embolization Inc.'s Nitinol Enhanced Device (NED).
This nitinol vascular embolization device has another shape memory material up its sleeve
July 2025 edition: The Surgical Robotics issue, featuring Capstan Medical, J&J and Zimmer Biomet
A photo of Capstan Medical's mitral valve implant, which uses nitinol.
Capstan Medical’s R&D head discusses the heart valve and robotics startup’s tech, engineering challenges and solutions, advice for others in medtech and how to join his team
An illustration of a neurosurgeon using a robotic endoscope to remove a brain tumor.
MDO Nitinol Innovation Special Report
“mdo
EXPAND YOUR KNOWLEDGE AND STAY CONNECTED
Get the latest medical device business news, application and technology trends.

DeviceTalks Weekly

See More >

MDO Digital Edition

Digital Edition

Subscribe to Medical Design & Outsourcing. Bookmark, share and interact with the leading medical design engineering magazine today.

MEDTECH 100 INDEX

Medtech 100 logo
Market Summary > Current Price
The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing.
DeviceTalks

DeviceTalks is a conversation among medical technology leaders. It's events, podcasts, webinars and one-on-one exchanges of ideas & insights.

DeviceTalks

New MedTech Resource

Medical Tubing

MassDevice

Mass Device

The Medical Device Business Journal. MassDevice is the leading medical device news business journal telling the stories of the devices that save lives.

Visit Website
MDO ad
Medical Design and Outsourcing
  • MassDevice
  • DeviceTalks
  • MedTech100 Index
  • Medical Tubing + Extrusion
  • Medical Design Sourcing
  • Drug Delivery Business News
  • Drug Discovery & Development
  • Pharmaceutical Processing World
  • R&D World
  • About Us/Contact
  • Advertise With Us
  • Subscribe to Print Magazine
  • Subscribe to our E-Newsletter
  • Listen to our Weekly Podcasts
  • Join our DeviceTalks Tuesdays Discussion

Copyright © 2025 WTWH Media, LLC. All Rights Reserved. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media LLC. Site Map | Privacy Policy | RSS

Search Medical Design & Outsourcing

  • Home
  • Medical Device Business
    • Mergers & Acquisitions
    • Financial
    • Regulatory
  • Applications
    • Cardiovascular
    • Devices
    • Imaging
    • Implantables
    • Medical Equipment
    • Orthopedic
    • Surgical
  • Technologies
    • Supplies and Components Index
    • Contract Manufacturing
    • Components
    • Electronics
    • Extrusions
    • Materials
    • Motion Control
    • Prototyping
    • Pumps
    • Tubing
  • MedTech Resources
    • Medtech Events in 2025
    • The 2024 Medtech Big 100
    • Medical Device Handbook
    • MedTech 100 Index
    • Subscribe to Print Magazine
    • DeviceTalks
    • Digital Editions
    • eBooks
    • Educational Assets
    • Manufacturer Search
    • Podcasts
    • Print Subscription
    • Webinars / Digital Events
    • Whitepapers
    • Voices
    • Views
    • Video
  • 2025 Leadership
    • 2024 Winners
    • 2023 Winners
    • 2022 Winners
    • 2021 Winners
  • Women in Medtech
  • Advertise
  • Subscribe