Epicenter’s ZeroTo510 Accelerator selects five medtech startups

Epicenter has selected five medtech startups to participate in its ZeroTo510 Accelerator, which supports early-stage medtech founders accelerating toward commercialization.

Epicenter is a Memphis-based nonprofit that helps startups grow their ventures.

Its ZeroTo510 Accelerator is a 13-week program designed to support medtech startups through essential development stages. Participating companies receive a $25,000 investment.

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“The companies that will define the next decade of healthcare are being built right now,” ZeroTo510 Director Olaf Schulz said in a statement shared with Medical Design & Outsourcing ahead of the announcement. “At ZeroTo510, we believe it is our responsibility to stay at the forefront of innovation, and this year’s cohort is a direct reflection of that commitment. These founders are attacking healthcare’s most pressing unmet needs, and we’re proud to put the full weight of our programming, network, and resources behind them.”

The 2026 cohort includes (the descriptions below come from ZeroTo510):

• Provision Surgical (Nashville, Tennessee): “Provision Surgical’s PAIR Guide uses AI to transform a patient’s medical scans into a live 3D model projected directly into the surgeon’s field of view through AR smart glasses — delivering real-time, patient-specific guidance during knee replacement surgery with sub-millimeter accuracy and no robot required.”
• OK2StandUP Inc. (Bedford, Pennsylvania): “OK2StandUP is tackling the nearly $30 billion annual burden of hospital-acquired pressure injuries by combining real-time physiological and EHR data to predict elevated risk and enable earlier intervention.”
• ConvertaTek (Memphis, Tennessee): “ConvertaTek has engineered a first-of-its-kind modular shoulder implant system that allows surgeons to seamlessly convert between anatomic and reverse total shoulder arthroplasty configurations, giving younger patients access to pain relief without sacrificing future surgical options.”
• Ravan Medical Co. (Houston, Texas): “Ravan Medical’s PulmVac is a compact, wearable chest drainage device that continuously monitors and manages pneumothorax with precision pressure sensing, freeing patients from bedside wall suction while giving clinicians objective, real-time data to guide treatment decisions.”
• CuffWay (Columbia, South Carolina): “CuffWay has developed the first automated, adaptive cuff-pressure controller for endotracheal and tracheostomy tubes, addressing a silent ICU epidemic of complications affecting 9 million intubated patients each year through sustained mismanagement of airway cuffs.”

Participants will receive training in areas like business planning, product development, regulatory landscapes, reimbursement and payment strategies, quality and manufacturing, pitching and fundraising.

The program ends in a demo day in Memphis on Dec. 10, 2026, where companies will showcase their technologies to investors, business leaders and ZeroTo510 alumni.

Epicenter says ZeroTo510 was created in 2012 through the Memphis Bioworks Foundation. The program has now included more than 50 companies that have collectively raised more than $120 million, including SweetBio, Hera Health and Corami.